1-Benzoyl-3-methyl-2,6-diphenyl-4-piperidone
نویسندگان
چکیده
In the title moleclue, C(25)H(23)NO(2), the 4-piperidone ring adopts a boat conformation. The mol-ecular conformation is stabilized by an intra-molecular C-H⋯O hydrogen bond. In the crystal, mol-ecules are connected through weak inter-molecular C-H⋯O hydrogen bonds.
منابع مشابه
Synthesis and biological activities of 2,6-diaryl-3-methyl-4-piperidone derivatives.
In the present study, a new series of 2,6-diaryl-3-methyl-4-piperidones was synthesized by Mannich reaction (condensation) of ethyl-methyl ketone, substituted aromatic aldehydes and ammonium acetate. Oximes and thiosemicarbazone derivatives of 2,6-diaryl-3-methyl-4-piperidones were synthesized by reaction with hydroxylamine hydrochloride and thiosemicarbazide respectively. The chemical structur...
متن کاملKeto-Enol-Tautomerism and Configurational Isomerism of 2,6-Disubstituted 4-Piperidone-3,5-dicarboxylates [1]
The dialkyl 2,6-dialkylsubstituted 4-piperidone-3,5-dicarboxylates were synthesized by a Mannich procedure. Depending on the substitution at the nitrogen keto-enol-tautomerism and a configurational isomerism at C 2 is observed. The structure o f the N-substituted piperidone 24 E (C 18H29N 0 5) has been determined by X-ray analysis: it is characterized by an enol structure o f the /?-ketoester a...
متن کاملEthyl 1-benzoyl-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate
In the title compound, C(27)H(25)NO(4), the tetra-hydro-pyridine ring adopts a half-chair conformation. The three phenyl rings form dihedral angles of 66.33 (7), 87.36 (8) and 36.90 (7)° with the least-squares plane through the tetra-hydro-pyridine ring. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯O hydrogen bond, generating an S(6) motif.
متن کامل1,3-Dimethyl-2,6-diphenylpiperidin-4-one
In the title moleclue, C(19)H(21)NO, the 4-piperidone ring adopts a chair conformation in which the two benzene rings and the methyl group attached to C atoms all have equatorial orientations. In the crystal structure, centrosymmetric dimers are formed through weak inter-molecular C-H⋯O hydrogen bonds [the dihedral angle between the aromatic rings is 58.51 (5)°].
متن کامل3,5-Dichlorophenyl 4-methylbenzoate
The structure of the title compound, C(14)H(10)Cl(2)O(2), resembles those of 3-chloro-phenyl 4-methyl-benzoate, 2,6-dichloro-phenyl 4-methyl-benzoate and 2,4-dichloro-phenyl 4-methyl-benzoate, with similar bond parameters. The dihedral angle between the benzene and benzoyl rings is 48.81 (6)°.
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